DSPP Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A25260-20, A25260-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IF-P, ELISA
Cross-reactivity: Human
Protein Weight: 131kDa
Observed Molecular Weight: 97kDa, 131kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1834
SWISS: Q9NZW4
Alternate Names: DPP; DSP; DGI1; DMP3; DFNA39; DSPP
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation, Cytoskeleton, Extracellular Matrix, Bone, Neuroscience, Calcium Signaling.
NCBI Alias: DSPP
Research Use Only