DVL1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24657-20, A24657-100
Citations, Manuals and MSDS Available upon request.
Background: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse
Protein Weight: 75kDa
Observed Molecular Weight: 85kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 1855
SWISS: O14640
Alternate Names: DVL; DRS2; DVL1L1; DVL1P1; DVL1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:2000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Translation Control, Regulation of eIF4 and p70 S6 Kinase, Signal Transduction, mTOR Signaling Pathway, Cell Biology Developmental Biology, Wnt-Catenin Signaling Pathway, Stem Cells.
NCBI Alias: DVL1
Research Use Only