EIF2B3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10262-20, A10262-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 50kDa
Observed Molecular Weight: 50kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8891
SWISS: Q9NR50
Alternate Names: EIF-2B; EIF2Bgamma; EIF2B3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Translation Control, Endocrine Metabolism, Insulin Receptor Signaling Pathway.
NCBI Alias: EIF2B3
Research Use Only