eIF4E Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0468-20, A0468-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human
Protein Weight: 25kDa
Observed Molecular Weight: 24kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1977
SWISS: P06730
Alternate Names: CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; eIF4E
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Translation Control, Regulation of eIF4 and p70 S6 Kinase, Protein phosphorylation, Signal Transduction, Endocrine Metabolism, Insulin Receptor Signaling Pathway, Immunology Inflammation, Cardiovascular, Angiogenesis.
NCBI Alias: EIF4E
Research Use Only