ELAC2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7128-20, A7128-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 92kDa
Observed Molecular Weight: 105kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 60528
SWISS: Q9BQ52
Alternate Names: ELC2; HPC2; COXPD17; ELAC2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Cell Biology Developmental Biology, Cell Cycle, Cell cycle inhibitors.
NCBI Alias: ELAC2
Research Use Only