EML4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16117-20, A16117-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 109kDa
Observed Molecular Weight: 120kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 27436
SWISS: Q9HC35
Alternate Names: C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120; EML4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Cytoskeleton, Microtubules.
NCBI Alias: EML4
Research Use Only