ENSA Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15665-20, A15665-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse
Protein Weight: 13kDa
Observed Molecular Weight: 13kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 2029
SWISS: O43768
Alternate Names: ARPP-19e; ENSA
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Neuroscience.
NCBI Alias: ENSA
Research Use Only