Fibrinogen alpha chain (FGA) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1453-20, A1453-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 95kDa
Observed Molecular Weight: 95kDa/60-70kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 2243
SWISS: P02671
Alternate Names: Fib2; Fibrinogen alpha chain (FGA)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cardiovascular, Blood, Serum Proteins.
NCBI Alias: FGA
Research Use Only