Fibroblast activation protein-α (FAP) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6349-20, A6349-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 88kDa
Observed Molecular Weight: 90kDa/95kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 2191
SWISS: Q12884
Alternate Names: FAPA; SIMP; DPPIV; FAPalpha; Fibroblast activation protein-α (FAP)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor biomarkers, Signal Transduction, Kinase, Cell Biology Developmental Biology, Cell Cycle, Ubiquitin.
NCBI Alias: FAP
Research Use Only