FOXO3A Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0102-20, A0102-100
Citations, Manuals and MSDS Available upon request.
Background: Enables DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and mitochondrial transcription factor activity. Involved in several processes, including mitochondrial transcription; positive regulation of muscle atrophy; and positive regulation of pri-miRNA transcription by RNA polymerase II. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway in absence of ligand; female gonad development; and neuronal stem cell population maintenance. Located in cytosol; mitochondrial outer membrane; and nucleus. Part of protein-containing complex. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and hemolymphoid system. Used to study dermoid cyst of ovary. Orthologous to human FOXO3 (forkhead box O3).
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 71kDa
Observed Molecular Weight: 80-90kDa
Immunogen: Recombinant protein (or fragment)
Species: Mouse
GeneID: 56484
SWISS: Q9WVH4
Alternate Names: Fkhr2; FKHRL1; Foxo3a; 1110048B16Rik; 2010203A17Rik; FOXO3A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics & Nuclear Signaling, Transcription Factors, Signal Transduction, G protein signaling, G2/M DNA Damage Checkpoint, MAPK-Erk Signaling Pathway, Cell Biology & Developmental Biology, Autophagy, Cell Cycle, G1/S Checkpoint, Endocrine & Metabolism, Insulin Receptor Signaling Pathway, Immunology & Inflammation, B Cell Receptor Signaling Pathway.
NCBI Alias: Foxo3
Research Use Only