FREM1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16603-20, A16603-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 244kDa
Observed Molecular Weight: 72kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 158326
SWISS: Q5H8C1
Alternate Names: BNAR; MOTA; TILRR; TRIGNO2; C9orf143; C9orf145; C9orf154; FREM1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology & Developmental Biology.
NCBI Alias: FREM1
Research Use Only