GDF15 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A25024-20, A25024-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.
Category: Polyclonal Antibodies
Applications: IF/ICC, ELISA
Cross-reactivity: Human
Protein Weight: 34kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 9518
SWISS: Q99988
Alternate Names: PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; GDF15
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Cytoskeleton, Extracellular Matrix, Bone, Growth factors, Immunology Inflammation, Cytokines, Cardiovascular, Heart, Hypertrophy.
NCBI Alias: GDF15
Research Use Only