GLE1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13207-20, A13207-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A) +RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A) +RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 80kDa
Observed Molecular Weight: 80kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 2733
SWISS: Q53GS7
Alternate Names: LCCS; CAAHC; CAAHD; GLE1L; LCCS1; hGLE1; GLE1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction.
NCBI Alias: GLE1
Research Use Only