GLI1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14675-20, A14675-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 118kDa
Observed Molecular Weight: 150kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 2735
SWISS: P08151
Alternate Names: GLI; PPD1; PAPA8; GLI1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Tumor suppressors, Signal Transduction, Cell Biology Developmental Biology, Neuroscience, Stem Cells.
NCBI Alias: GLI1
Research Use Only