GLI2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6510-20, A6510-100
Citations, Manuals and MSDS Available upon request.
Background: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Acts upstream of or within several processes, including animal organ development; chordate embryonic development; and regulation of smoothened signaling pathway. Located in several cellular components, including axoneme; ciliary tip; and nuclear speck. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and jaw. Human ortholog (s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2) .
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 168kDa
Observed Molecular Weight: 90kDa
Immunogen: Recombinant protein (or fragment) .
Species: Mouse
GeneID: 14633
SWISS: P10070
Alternate Names: GLI2; CJS; HPE9; PHS2; THP1; THP2; Gli2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics & Nuclear Signaling, Transcription Factors, Signal Transduction, Cell Biology & Developmental Biology, Hedgehog Signaling Pathway, Neuroscience, Stem Cells.
NCBI Alias: Gli2
Research Use Only