GNAQ Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14736-20, A14736-100
Citations, Manuals and MSDS Available upon request.
Background: This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 42kDa
Observed Molecular Weight: 42kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 2776
SWISS: P50148
Alternate Names: GAQ; SWS; CMAL; CMC1; G-ALPHA-q; GNAQ
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Translation Control, Regulation of eIF4 and p70 S6 Kinase, Cancer, Signal Transduction, G protein signaling, Small G proteins, G-Protein-Coupled Receptors Signaling to MAPK Erk, PI3K-Akt Signaling Pathway, mTOR Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton, Microtubules, Actins, ESC Pluripotency and Differentiation, Endocrine Metabolism, AMPK Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Blood, Heart.
NCBI Alias: GNAQ
Research Use Only