GPNMB Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14270-20, A14270-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 64kDa
Observed Molecular Weight: 64kDa/90-120kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 10457
SWISS: Q14956
Alternate Names: NMB; HGFIN; PLCA3; GPNMB
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor immunology, Tumor-associated antigens, Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway.
NCBI Alias: GPNMB
Research Use Only