H2-Aa Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18325-20, A18325-100
Citations, Manuals and MSDS Available upon request.
Background: Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system; retina; and thymus primordium. Human ortholog (s) of this gene implicated in several diseases, including autoimmune disease (multiple) ; gastrointestinal system cancer (multiple) ; glomerulonephritis (multiple) ; hematologic cancer (multiple) ; and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1).
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 28kDa
Observed Molecular Weight: 28kDa
Immunogen: Recombinant protein (or fragment)
Species: Mouse
GeneID: 14960
SWISS: P14434
Alternate Names: Ia1; H2Aa; Ia-1; H-2Aa; Aalpha; IAalpha; I-Aalpha; H2-Aa
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: H2-Aa
Research Use Only