HDAC6 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A27908-20, A27908-100
Citations, Manuals and MSDS Available upon request.
Background: Enables several functions, including cytoskeletal protein binding activity; protein lysine deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of type 2 mitophagy; protein destabilization; and tubulin deacetylation. Acts upstream of or within several processes, including aggresome assembly; neuron projection morphogenesis; and protein modification process. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of cytoplasmic ubiquitin ligase complex. Is expressed in several structures, including central nervous system; early embryo; gut gland; lung; and metanephros. Human ortholog (s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia and polycystic liver disease 1. Orthologous to human HDAC6 (histone deacetylase 6) .
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 126kDa
Observed Molecular Weight: 140kDa
Immunogen: Recombinant protein (or fragment) .
Species: Mouse
GeneID: 15185
SWISS: Q9Z2V5
Alternate Names: Hd6; Sfc6; Hdac5; mHDA2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:3000 - 1:18000 IF/ICC, 1:100 - 1:200 IHC-P, 1:200 - 1:800 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes AcetylationStem Cells Signaling Pathways Wnt HDACsEpigenetics and Nuclear Signaling Chromatin Modifying Enzymes Acetylation HDACs Class II / Hda1 Class
NCBI Alias: HDAC6
Research Use Only