HEY2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15143-20, A15143-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 36kDa
Observed Molecular Weight: 36kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 23493
SWISS: Q9UBP5
Alternate Names: GRL; CHF1; HRT2; HERP1; HESR2; bHLHb32; GRIDLOCK; HEY2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Stem Cells, Cardiovascular, Heart, Cardiogenesis.
NCBI Alias: HEY2
Research Use Only