HSPB8/HSP22 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2514-20, A2514-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 22kDa
Observed Molecular Weight: 22kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 26353
SWISS: Q9UJY1
Alternate Names: H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22; HSPB8/HSP22
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 IF-P, 1:50 - 1:200 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: HSPB8
Research Use Only