HTR1B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18285-20, A18285-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine) . Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 44kDa
Observed Molecular Weight: 44kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 3351
SWISS: P28222
Alternate Names: S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT-1B; 5-HT1DB; 5-HT-1D-beta; HTR1B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Endocrine Metabolism, Endocrine and metabolic diseases, Obesity, Neuroscience.
NCBI Alias: HTR1B
Research Use Only