IFI16 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24865-20, A24865-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, FC, ELISA
Cross-reactivity: Human
Protein Weight: 75kDa/82kDa/88kDa
Observed Molecular Weight: 95kDa, 98kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 3428
SWISS: Q16666
Alternate Names: IFI16; IFNGIP1; PYHIN2; gamma-interferon-inducible protein 16
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 FC, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics & Nuclear Signaling, Transcription Factors, DNA Damage & Repair, RNA Binding, Cancer, Tumor suppressors, p53 pathway, Cell Biology & Developmental Biology, Apoptosis, Cell Cycle, Cell cycle inhibitors, Endocrine & Metabolism.
NCBI Alias: IFI16
Research Use Only