IFNGR2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14221-20, A14221-100
Citations, Manuals and MSDS Available upon request.
Background: This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 38kDa
Observed Molecular Weight: 38kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 3460
SWISS: P38484
Alternate Names: AF-1; IFGR2; IMD28; IFNGT1; IFNGR2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Endocrine Metabolism, Endocrine and metabolic diseases, Obesity, Immunology Inflammation, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway, Stem Cells.
NCBI Alias: IFNGR2
Research Use Only