IGFBP3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A27971-20, A27971-100
Citations, Manuals and MSDS Available upon request.
Background: Enables fibronectin binding activity and insulin-like growth factor binding activity. Involved in osteoblast differentiation. Acts upstream of or within several processes, including positive regulation of signal transduction; regulation of glucose metabolic process; and type B pancreatic cell proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; early embryo; gonad; and limb. Human ortholog (s) of this gene implicated in several diseases, including Alzheimer's disease; Turner syndrome; diabetes mellitus (multiple) ; prostate cancer; and transitional cell carcinoma. Orthologous to human IGFBP3 (insulin like growth factor binding protein 3) .
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 32kDa
Observed Molecular Weight: 39-45kDa (glycosylated), 29 kDa (non-glycosylated)
Immunogen: Recombinant protein (or fragment) .
Species: Mouse
GeneID: 16009
SWISS: P47878
Alternate Names: IGFBP-3; IGgfbp3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1500 - 1:6000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Growth factors, Endocrine Metabolism, Endocrine and metabolic diseases, Diabetes, Obesity, Cardiovascular, Angiogenesis.
NCBI Alias: Igfbp3
Research Use Only