Integrin beta 1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A27421-20, A27421-100
Citations, Manuals and MSDS Available upon request.
Background: Enables integrin binding activity involved in cell-matrix adhesion and signaling receptor activity. Contributes to laminin binding activity. Involved in several processes, including basement membrane organization; cellular response to low-density lipoprotein particle stimulus; and regulation of synapse pruning. Acts upstream of or within with a negative effect on reactive gliosis and regulation of spontaneous synaptic transmission. Acts upstream of or within several processes, including circulatory system development; neuron projection morphogenesis; and regulation of transmembrane transport. Located in several cellular components, including intercalated disc; myelin sheath abaxonal region; and sarcolemma. Part of integrin alpha7-beta1 complex and integrin alpha9-beta1 complex. Is active in Schaffer collateral - CA1 synapse; cerebellar climbing fiber to Purkinje cell synapse; and synaptic membrane. Colocalizes with cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and heart. Used to study Hirschsprung's disease. Orthologous to human ITGB1 (integrin subunit beta 1) .
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 88kDa
Observed Molecular Weight: 115kDa/135kDa
Immunogen: Recombinant protein (or fragment) .
Species: Mouse
GeneID: 16412
SWISS: P09055
Alternate Names: CD29; Fnrb; gpIIa; Gm9863; 4633401G24Rik
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Neuroscience, cell type markers, neural stem cell markers
NCBI Alias: Itgb1
Research Use Only