KAT6B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A17116-20, A17116-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 231kDa
Observed Molecular Weight: 280kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 23522
SWISS: Q8WYB5
Alternate Names: qkf; MORF; MOZ2; GTPTS; MYST4; ZC2HC6B; querkopf; KAT6B
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones.
NCBI Alias: KAT6B
Research Use Only