KCNQ2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1917-20, A1917-100
Citations, Manuals and MSDS Available upon request.
Background: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1) . At least five transcript variants encoding five different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 96kDa
Observed Molecular Weight: 95kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 3785
SWISS: O43526
Alternate Names: EBN; BFNC; DEE7; EBN1; ENB1; HNSPC; KV7.2; KCNA11; KCNQ2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Neuroscience, Neurodegenerative Diseases.
NCBI Alias: KCNQ2
Research Use Only