[KD Validated] CYB5R3 Rabbit pAb - A24755

[KD Validated] CYB5R3 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A24755-20, A24755-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Rat

Protein Weight: 31kDa/34kDa/38kDa

Observed Molecular Weight: 30-38kDa/38kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 1727

SWISS: P00387

Alternate Names: CYB5R3; B5R; DIA1; cytochrome b5 reductase 3

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine & Metabolism, Lipid Metabolism, Cholesterol Metabolism, Drug metabolism, Cardiovascular, Lipids.

NCBI Alias: CYB5R3

Research Use Only