[KD Validated] IGF1R Rabbit pAb - A0243

[KD Validated] IGF1R Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A0243-20, A0243-100

Citations, Manuals and MSDS Available upon request.

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 155kDa

Observed Molecular Weight: 100kDa/

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 3480

SWISS: P08069

Alternate Names: IGFR; CD221; IGFIR; JTK13; 1R

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Protein phosphorylation, Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Apoptosis, Growth factors, ESC Pluripotency and Differentiation, Immunology Inflammation, CDs, Cardiovascular, Angiogenesis.

NCBI Alias: IGF1R

Research Use Only