[KD Validated] TRIM21/SS-A Rabbit pAb - A1957

[KD Validated] TRIM21/SS-A Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A1957-20, A1957-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 54kDa

Observed Molecular Weight: 50kDa//54kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 6737

SWISS: P19474

Alternate Names: SSA; RO52; SSA1; RNF81; Ro/SSA; TRIM21/SS-A

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Immunology Inflammation.

NCBI Alias: TRIM21

Research Use Only