[KD Validated] YTHDC2 Rabbit pAb - A24219

[KD Validated] YTHDC2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A24219-20, A24219-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.

Category: Polyclonal Antibodies

Applications: WB, IP, IF-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 160kDa

Observed Molecular Weight: 170kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 64848

SWISS: Q9H6S0

Alternate Names: CAHL; hYTHDC2; YTHDC2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cell Biology Developmental Biology.

NCBI Alias: YTHDC2

Research Use Only