KDM6A Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A8159-20, A8159-100
Citations, Manuals and MSDS Available upon request.
Background: Enables DNA binding activity; histone H3-tri/di-methyl-lysine-27 demethylase activity; and identical protein binding activity. Involved in chromatin remodeling. Acts upstream of or within several processes, including chordate embryonic development; embryonic morphogenesis; and histone H3-K27 demethylation. Located in nucleus. Part of histone methyltransferase complex. Is expressed in several structures, including early conceptus; gonad; liver; lung; and spleen. Used to study chronic myelomonocytic leukemia. Human ortholog (s) of this gene implicated in several diseases, including Kabuki syndrome; bladder urothelial carcinoma; gastrointestinal system cancer (multiple) ; lung carcinoma (multiple) ; and triple-receptor negative breast cancer. Orthologous to human KDM6A (lysine demethylase 6A).
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 154kDa/157kDa
Observed Molecular Weight: 180kDa
Immunogen: Recombinant protein (or fragment)
Species: Mouse
GeneID: 22289
Alternate Names: Utx; KDM6A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics & Nuclear Signaling, Chromatin Modifying Enzymes, Demethylation.
NCBI Alias: Kdm6a
Research Use Only