Kdm6b Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12763-20, A12763-100
Citations, Manuals and MSDS Available upon request.
Background: Enables beta-catenin binding activity; histone H3-tri/di-methyl-lysine-27 demethylase activity; and sequence-specific DNA binding activity. Involved in several processes, including histone H3-K27 demethylation; mesodermal cell differentiation; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to hydrogen peroxide; histone demethylation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including brain; gut; liver; metanephros; and olfactory epithelium. Orthologous to human KDM6B (lysine demethylase 6B).
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 176kDa
Observed Molecular Weight: 170kDa
Immunogen: Recombinant protein (or fragment)
Species: Mouse
GeneID: 216850
Alternate Names: Jmjd3; 1700064E03Rik; Kdm6b
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics & Nuclear Signaling, Chromatin Modifying Enzymes, Demethylation, Immunology & Inflammation.
NCBI Alias: Kdm6b
Research Use Only