[KO Validated] α-Catenin Rabbit pAb - A5635

[KO Validated] α-Catenin Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5635-20, A5635-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 100kDa

Observed Molecular Weight: 115kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 1495

SWISS: P35221

Alternate Names: MDBS2; MDPT2; CAP102; in

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cadherins, Tight Junctions, Cytoskeleton, Microfilaments, Wnt -Catenin Signaling Pathway, Stem Cells.

NCBI Alias: CTNNA1

Research Use Only