[KO Validated] Annexin A6/Annexin VI Rabbit pAb - A18069

[KO Validated] Annexin A6/Annexin VI Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18069-20, A18069-100

Citations, Manuals and MSDS Available upon request.

Background: Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 76kDa

Observed Molecular Weight: 76kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 309

SWISS: P08133

Alternate Names: p68; p70; ANX6; CBP68; CPB-II; VI

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Endocrine Metabolism, Lipid Metabolism, Neuroscience, Calcium Signaling.

NCBI Alias: ANXA6

Research Use Only