[KO Validated] APEH Rabbit pAb - A5893

[KO Validated] APEH Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5893-20, A5893-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Category: Polyclonal Antibodies

Applications: WB, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 81kDa

Observed Molecular Weight: 81kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 327

SWISS: P13798

Alternate Names: APH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2; EH

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Tumor suppressors, Cell Biology Developmental Biology, Ubiquitin.

NCBI Alias: APEH

Research Use Only