[KO Validated] BUB1 Rabbit pAb - A18053

[KO Validated] BUB1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18053-20, A18053-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 122kDa

Observed Molecular Weight: 133kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 699

SWISS: O43683

Alternate Names: BUB1A; BUB1L; hBUB1; MCPH30; B1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Kinase, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Cycle.

NCBI Alias: BUB1

Research Use Only