[KO Validated] CDK7 Rabbit pAb - A12942

[KO Validated] CDK7 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A12942-20, A12942-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 39kDa

Observed Molecular Weight: 40kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 1022

SWISS: P50613

Alternate Names: CAK; CAK1; HCAK; MO15; STK1; CDKN7; p39MO15; K7

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Signal Transduction, Kinase, Serine threonine kinases, Cell Biology Developmental Biology, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint.

NCBI Alias: CDK7

Research Use Only