[KO Validated] FUS Rabbit pAb - A5921

[KO Validated] FUS Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5921-20, A5921-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 53kDa

Observed Molecular Weight: 70kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 2521

SWISS: P35637

Alternate Names: TLS; ALS6; ETM4; FUS1; POMP75; altFUS; HNRNPP2; US

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:100 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, RNA Binding, Cancer, Signal Transduction.

NCBI Alias: FUS

Research Use Only