[KO Validated] GRK2 Rabbit pAb - A1662

[KO Validated] GRK2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A1662-20, A1662-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 80kDa

Observed Molecular Weight: 80kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 156

SWISS: P25098

Alternate Names: BARK1; ADRBK1; BETA-ARK1; K2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, G-Protein-Coupled Receptors Signaling to MAPK Erk, Kinase, Serine threonine kinases, Immunology Inflammation, Neuroscience.

NCBI Alias: GRK2

Research Use Only