[KO Validated] HDAC8 Rabbit pAb - A5829

[KO Validated] HDAC8 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5829-20, A5829-100

Citations, Manuals and MSDS Available upon request.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 42kDa

Observed Molecular Weight: 45kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 55869

SWISS: Q9BY41

Alternate Names: HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1; C8

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Immunology Inflammation, NF-kB Signaling Pathway, Stem Cells, Cardiovascular, Heart, Hypertrophy.

NCBI Alias: HDAC8

Research Use Only