[KO Validated] HMGB1 Rabbit pAb - A2553

[KO Validated] HMGB1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A2553-20, A2553-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 25kDa

Observed Molecular Weight: 29kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 3146

SWISS: P09429

Alternate Names: HMG1; HMG3; HMG-1; SBP-1; HMGB1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:5000 IHC-P, 1:100 - 1:400 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cell Biology Developmental Biology, Apoptosis.

NCBI Alias: HMGB1

Research Use Only