[KO Validated] Integrin alpha 2 (ITGA2/CD49b) Rabbit pAb - A7629

[KO Validated] Integrin alpha 2 (ITGA2/CD49b) Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A7629-20, A7629-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 129kDa

Observed Molecular Weight: 150kDa

Immunogen: Synthetic peptide .

Species: Human

GeneID: 3673

SWISS: P17301

Alternate Names: BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; b)

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Endocrine Metabolism, Immunology Inflammation, CDs.

NCBI Alias: ITGA2

Research Use Only