[KO Validated] NADPH oxidase 4 (NOX4) Rabbit pAb - A11274

[KO Validated] NADPH oxidase 4 (NOX4) Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A11274-20, A11274-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 67kDa

Observed Molecular Weight: 65kDa

Immunogen: Synthetic peptide

Species: Human

GeneID: 50507

SWISS: Q9NPH5

Alternate Names: KOX; KOX-1; RENOX; 4)

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol,  preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Cell Biology Developmental Biology, Endocrine Metabolism, Drug metabolism, Immunology Inflammation, Cardiovascular, Blood, Heart, Cardiovascular diseases, Heart disease.

NCBI Alias: NOX4

Research Use Only