[KO Validated] PDCD6 Rabbit pAb - A6685

[KO Validated] PDCD6 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A6685-20, A6685-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Category: Polyclonal Antibodies

Applications: WB, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 22kDa

Observed Molecular Weight: 16kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 10016

SWISS: O75340

Alternate Names: ALG2; ALG-2; PEF1B; D6

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Neuroscience, Calcium Signaling.

NCBI Alias: PDCD6

Research Use Only