[KO Validated] PNP Rabbit pAb - A19885

[KO Validated] PNP Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A19885-20, A19885-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 32kDa

Observed Molecular Weight: 30kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 4860

SWISS: P00491

Alternate Names: NP; PUNP; PRO1837

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Neuroscience, Neurodegenerative Diseases.

NCBI Alias: PNP

Research Use Only