[KO Validated] SEC61B Rabbit pAb - A15788

[KO Validated] SEC61B Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A15788-20, A15788-100

Citations, Manuals and MSDS Available upon request.

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 10kDa

Observed Molecular Weight: 12kDa

Immunogen: Synthetic peptide

Species: Human

GeneID: 10952

SWISS: P60468

Alternate Names: SEC61B; 1B

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Signal Transduction.

NCBI Alias: SEC61B

Research Use Only