[KO Validated] SIRT3 Rabbit pAb - A5718

[KO Validated] SIRT3 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5718-20, A5718-100

Citations, Manuals and MSDS Available upon request.

Background: SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 44kDa

Observed Molecular Weight: 28kDa

Immunogen: Synthetic peptide .

Species: Human

GeneID: 23410

SWISS: Q9NTG7

Alternate Names: SIR2L3; T3

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling.

NCBI Alias: SIRT3

Research Use Only