LATS2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16249-20, A16249-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 120kDa
Observed Molecular Weight: 150kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 26524
SWISS: Q9NRM7
Alternate Names: KPM; LATS2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Signal Transduction, Kinase, Serine threonine kinases, Cell Biology Developmental Biology.
NCBI Alias: LATS2
Research Use Only